• 介紹：

   Chlorogenic acid (3-O-Caffeoylquinic acid) 是金銀花中的主要酚類(lèi)化合物。Chlorogenic acid 具有一些重要作用，如抗氧化活性，抗菌，保肝，心臟保護(hù)，抗炎，解熱，神經(jīng)保護(hù)，抗肥胖，抗病毒，抗微生物，抗高血壓。

• 熔點(diǎn)： 210°C

• 沸點(diǎn)： 665°Cat760mmHg

• 比旋光度： ?-35.0°～ -38.0°(C=1, H2O)

• 外觀： 白色至淺黃褐色粉末

• 溶解性： DMSO  :  100  mg/mL  (282.24  mM;  Need  ultrasonic)
  
  H2O  :  ≥  20  mg/mL  (56.45  mM)

• 儲(chǔ)存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。

• 90. [4.7] Qian-Ni Yang et al."Characterization, Antioxidant Capacity, and Anti-Inflammatory Activity of Polyphenol-Enriched Extracts Obtained from Unripe, Mature, and Overripe Fruits of Red-Fleshed Kiwifruit Cultivars."Foods.2024 Jan;13(18):2860

• 89. [4.8] Guoying Zhang et al."Caffeoylquinic acids from Silphium perfoliatum L. show hepatoprotective effects on cholestatic mice by regulating enterohepatic circulation of bile acids."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;337:118870

• 88. [4.9] Zhongda Cao et al."Baicalin Inhibits FIPV Infection In Vitro by Modulating the PI3K-AKT Pathway and Apoptosis Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(18):9930

• 87. [5.6] Chunte Feng et al."Rosmarinic acid separation from Perilla frutescens leaf extract utilizing acid-resistant magnetic molecularly imprinted polymers with boronate affinity."INDUSTRIAL CROPS AND PRODUCTS.2024 Dec;222:119582

• 86. [6.2] Jing Zhang et al."Zinc oxide nanoparticles reduce cadmium accumulation in hydroponic lettuce (Lactuca sativa L.) by increasing photosynthetic capacity and regulating phenylpropane metabolism."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Oct;285:117033

• 85. [6.5] Wen Deng et al."Comparative analysis of phenolic compounds in different thinned unripe kiwifruits and their biological functions."Food Chemistry-X.2024 Dec;24:101815

• 84. [3.1] Mengyu Qian et al."A comprehensive quality evaluation strategy for ReDuNing injection by integrating UPLC-Orbitrap MS/MS profile and biological potency combined with multivariate statistical analysis."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024

• 83. [3.4] Wenzhai Li et al."Metabolomics-based profiling of anti-inflammatory compounds from Mentha spicata in shanghe, China."Heliyon.2024 Aug;10:

• 82. [3.8] Xuemei Xiao et al."Development of a high-performance liquid chromatography method for simultaneous quantification of sixteen polyphenols and application to tomato."JOURNAL OF CHROMATOGRAPHY A.2024 Aug;:465254

• 81. [5.6] Chenfei Lu et al."Multiplex Approach of Metabolomic and Transcriptomic Reveals the Biosynthetic Mechanism of Light-induced Flavonoids and CGA in Chrysanthemum."INDUSTRIAL CROPS AND PRODUCTS.2024 Dec;221:119420

• 80. [7] Mengling Wang et al."AI-driven determination of active compounds and investigation of multi-pharmacological effects of Chrysanthemi Flos."COMPUTERS IN BIOLOGY AND MEDICINE.2024 Sep;180:108985

• 79. [8.5] Ruolan Song et al."Correlation analysis and modeling application from objective indicators to subjective evaluation of scented tea: A case study of rose tea."FOOD CHEMISTRY.2025 Jan;462:140963

• 78. [8.5] Wangsheng Sun et al."Effect of sequential fermentation with indigenous non-Saccharomyces cerevisiae combinations and Saccharomyces cerevisiae on the chemical composition and aroma compounds evolution of kiwifruit wine."FOOD CHEMISTRY.2024 Dec;460:140758

• 77. [4.7] Wanyu Dong et al."Evaluation of Pre-Harvest Nutrient Composition and Functional Active Substances in Various Lotus Roots."Foods.2024 Jul; 13(14): 2297

• 76. [4.8] Yinping Cao et al."Cyclic variable temperature conditioning-maintained storage quality of sweet potatoes by enhancing antioxidant activity."Food Bioscience.2024 Jul;:104689

• 75. [6.5] Gaozhong Yang et al."Effects of anaerobic treatment on the non-volatile ceomponents and angiotensin-converting enzyme (ACE) inhibitory activity of purple-colored leaf tea."Food Chemistry-X.2024 Jul;:101649

• 74. [6.5] Ziwei Wang et al."Combined metabolomics and bioactivity assays kernelby-productsof two native Chinese cherry species: The sources of bioactive nutraceutical compounds."Food Chemistry-X.2024 Oct;23:101625

• 73. [8.5] Changling Wu et al."Fractionation of phenolic compounds from hickory by-products using solid phase extraction-sonication: Chemical composition, antioxidant and antimicrobial activity."FOOD CHEMISTRY.2024 Dec;460:140633

• 72. [4.9] Xiaoran Zhao et al."Constructing a hydrogel based on self-assembly properties of glycyrrhizic acid: A drug delivery system with digestive tract responsive."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2024 Sep;697:134497

• 71. [7.7] Yufeng He et al."Influence of EGCG oxidation on inhibitory activity against the SARS-CoV-2 main protease."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Aug;274:133451

• 70. [8.5] Xiaohui Wu et al."Introducing Bacillus natto and Propionibacterium shermanii into soymilk fermentation: A promising strategy for quality improvement and bioactive peptide production during in vitro digestion."FOOD CHEMISTRY.2024 Oct;455:139585

• 69. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal

• 68. [IF=2.9] Wang Miaomiao et al."Effect of chemical components on color variation during processing of Crataegi Fructus."FOOD SCIENCE AND BIOTECHNOLOGY".2024 May;:1-11

• 67. [IF=4.3] Ju Li et al."Evaluation of nutritional composition, biochemical, and quality attributes of different varieties of tomato (Solanum lycopersicum L.)."JOURNAL OF FOOD COMPOSITION AND ANALYSIS".2024 Aug;132:106384

• 66. [IF=4.6] Qundong Liu et al."Quality Evaluation of Lonicerae Flos Produced in Southwest China Based on HPLC Analysis and Antioxidant Activity."MOLECULES".2024 Jan;29(11):2560

• 65. [IF=9.5] Huiling Zhong et al."Deferoxamine-Loaded Injectable Chitosan-Grafted Chlorogenic Acid/Oxidized Hyaluronic Acid Hybrid Hydrogel with Antibacterial, Anti-inflammatory, and Angiogenesis-Promoting Properties for Diabetic Wound Repair."ACS Applied Materials &

• 64. [IF=3.3] YueHong Zhao et al."Enhanced phenolic content and antioxidant activity of broad bean natto following simulated in vitro digestion."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY".2024 Apr;59(5):2873-2883

• 63. [IF=3.9] Junru Wang et al."Protective effects of sugarcane polyphenol against UV-B-induced photoaging in Balb/c mouse skin: Antioxidant, anti-inflammatory, and anti-glycosylation Effects."JOURNAL OF FOOD SCIENCE".2024 Apr;:

• 62. [IF=4.6] Chen Sun et al."Mechanism of Mulberry Leaves and Black Sesame in Alleviating Slow Transit Constipation Revealed by Multi-Omics Analysis."MOLECULES".2024 Jan;29(8):1713

• 61. [IF=4.8] Hongyan Tan et al."A rhodamine 110 loaded and molecularly imprinted polymers coated millipore filter membrane-based fluorescent sensor for sensitive and selective caffeic acid detection."MICROCHEMICAL JOURNAL".2024 Jun;201:110588

• 60. [IF=5.4] Rui Guo et al."Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118159

• 59. [IF=8.1] Yaxin Wang et al."Water-in-oil Pickering emulsion using ergosterol as an emulsifier solely."FOOD RESEARCH INTERNATIONAL".2024 Jun;186:114374

• 58. [IF=8.8] Yang Liu et al."Novel assaying method for the accurate and rapid analysis of antioxidant total capacity based on hexachloroiridate(IV)."FOOD CHEMISTRY".2024 Sep;451:139492

• 57. [IF=5.2] Pengfei Bi et al."Characterization of the effect of non-Saccharomyces cerevisiaes on the non-volatile constituents and volatile profiles of low-alcoholic pomegranate beverages."Food Bioscience".2024 Jun;59:103870

• 56. [IF=5.9] Shufang Yang et al."Unraveling the variations and relationships between phytochemical constituents and anti-inflammatory potentials of three Zanthoxylum species through metabolomics and explainable machine learning."INDUSTRIAL CROPS AND PRODUCTS".2024 Jun

• 55. [IF=9.9] Zhangtie Wang et al."Chrysanthemum as a remarkable edible flower resource with anti-glycation effects: Representative variety differences, phenolic compositions, and the interaction mechanism."Food Frontiers".2024 Mar;:

• 54. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222

• 53. [IF=1.6] Liu Huimin et al."Identification and Characterization of the Chemical Constituents of Qianlie Shule Capsules by UPLC-Q-Orbitrap-MS/MS."JOURNAL OF AOAC INTERNATIONAL".2024 Feb;:

• 52. [IF=3.3] Zheyong Wang et al."A comprehensive strategy for quality evaluation of Changan powder by fingerprinting combined with rapid qualitative and quantitative multi-ingredients profiling."PHYTOCHEMICAL ANALYSIS".2024 Feb;:

• 51. [IF=4.3] Yi Jiang et al."Shading in fruit changes the polyphenol accumulation of pellicle by regulating activity of key enzymes and expression of their gene related polyphenol anabolism of Juglans sigillata Dode."SCIENTIA HORTICULTURAE".2024 Apr;329:113017

• 50. [IF=4.3] Xin Guan et al."Variation of taste and odor compounds in tea beverage after microbial fermentation by HPLC–MS, GC×GC–O–MS, GC–MS, and sensory evaluation."JOURNAL OF FOOD COMPOSITION AND ANALYSIS".2024 Apr;128:106075

• 49. [IF=4.9] Huang Hefei et al."Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome."Chinese Medicine".2024 Dec;19(1):1-17

• 48. [IF=5.2] Dan Wu et al."Optimizing the Solvent Selection of the Ultrasound-Assisted Extraction of Sea Buckthorn (Hippophae rhamnoides L.) Pomace: Phenolic Profiles and Antioxidant Activity."Foods".2024 Jan;13(3):482

• 47. [IF=5.4] Yingxue Guo et al."Integrated network pharmacological analysis revealed that Smilax glabra Roxb. alleviates IMQ-induced psoriatic skin inflammation through regulating T cell immune response."JOURNAL OF ETHNOPHARMACOLOGY".2024 May;325:117836

• 46. [IF=7] Xiaomei Dai et al."Metabolism of Phenolic Compounds and Antioxidant Activity in Different Tissue Parts of Post-Harvest Chive (Allium?schoenoprasum L.)."Antioxidants".2024 Mar;13(3):279

• 45. [IF=7.5] Si-Yu Zhai et al."Gynura procumbens and selected metabolites: Amelioration of depressive-like behaviors in mice and risperidone-induced hyperprolactinemia in rats."BIOMEDICINE & PHARMACOTHERAPY".2024 Apr;173:116361

• 44. [IF=7.9] Wenxia Li et al."Ethanol Extract of Eclipta prostrata induces Multiple Myeloma Ferroptosis via Keap1/Nrf2/HO-1 Axis."PHYTOMEDICINE".2024 Feb;:155401

• 43. [IF=8.4] Yixin Suo et al."Fluorescent sensor based on CdTe-QDs @ N-CDs complexes for visual identification of goji berries origin."SENSORS AND ACTUATORS B-CHEMICAL".2024 May;406:135438

• 42. [IF=8.8] Qiaochun Chen et al."Effects of seasoning addition and cooking conditions on the formation of free and protein-bound heterocyclic amines and advanced glycation end products in braised lamb."FOOD CHEMISTRY".2024 Feb;:138850

• 41. [IF=1.8] Qin Fan et al."Integration of metabolomics and network pharmacology technology to explain the effect mechanisms of Danggui Buxue decoction in vascular dementia."BIOMEDICAL CHROMATOGRAPHY.2024 Jan;:e5822

• 40. [IF=3.3] Jie Zhang et al."Quality evaluation of Lonicerae Japonicae Flos from different origins based on high-performance liquid chromatography (HPLC) fingerprinting and multicomponent quantitative analysis combined with chemical pattern recognition."PHYTOCHEMICAL

• 39. [IF=5.4] Yingqiu Shi et al."Effective constituents and protective effect of Mudan granules against Schwann cell injury."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117692

• 38. [IF=8.1] Ning Yue et al."Imidacloprid triggered changes in strawberry fruits on edible quality and phenolic profiles by applied at two growth stages."FOOD RESEARCH INTERNATIONAL.2024 Mar;179:114031

• 37. [IF=8.4] Mei Su et al."Investigation of the Microstructure and Dynamical Evolution Following Gradient Hydration of Deep Eutectic Solvent, with Application to Polyphenol Extraction."ACS Sustainable Chemistry & Engineering.2024;XXXX(XXX):XXX-XXX

• 36. [IF=2.9] Min Huang et al."Effects of electron beam irradiation on microbial load and physicochemical qualities of Ligusticum chuanxiong Hort."RADIATION PHYSICS AND CHEMISTRY.2024 Apr;217:111508

• 35. [IF=3.7] Turkson Antwi Boasiako et al."Innovative Bicultured Lactic–Acetic Acid Co-fermentation Improves Jujube Puree’s Functionality and Volatile Compounds."Fermentation-Basel.2024 Jan;10(1):71

• 34. [IF=4.1] Liuyu Ye et al."In vitro digestion and colonic fermentation characteristics of media milled purple sweet potato particle-stabilized Pickering emulsions."JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE.2024 Jan;:

• 33. [IF=4.6] Xinhe Wang et al."Analysis of Polyphenol Extract from Hazel Leaf and Ameliorative Efficacy and Mechanism against Hyperuricemia Zebrafish Model via Network Pharmacology and Molecular Docking."MOLECULES.2024 Jan;29(2):317

• 32. [IF=5.2] Hazem Golshany et al."Comparative extraction and antioxidant potential of bioactive compounds from Fucus vesiculosus: Kinetic modeling and UPLC-Q-TOF-MS phenolic profiling."Food Bioscience.2024 Jan;:103575

• 31. [IF=3.1] Liang Yao et al."Characterization and quality evaluation of QiXueShuFu Decoction based on fingerprint and ultra-performance liquid chromatography-quadrupole-orbitrap mass spectrometry."JOURNAL OF SEPARATION SCIENCE.2023 Dec;:2300606

• 30. [IF=3.4] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Xiaoyao Wan by UPLC-Q-Orbitrap-MS, HS-SPME-GC-MS and HS-GC-IMS."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024 Feb;239:115910

• 29. [IF=4] Lewen Xiong et al."Study on Antipyretic Properties of Phenolics in Lonicerae Japonicae Flos Based on Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry Combined with Network Pharmacology."JOURNAL OF FOOD BIOCHEMISTRY.2023;2023:8883860

• 28. [IF=6] Rui Wang et al."Network Pharmacology-Based Approach reveals that Fructus mume exerts Therapeutic Effects against Ulcerative Colitis via the AGE/RAGE Signaling Pathway."Arabian Journal of Chemistry.2023 Dec;:105534

• 27. [IF=6] Meiqi Liu et al."The effect of honey as an excipient in the processing of traditional chinese medicine based on chemical profiling, artificial neural network, and virtual screening: Cortex Mori as an example."Arabian Journal of Chemistry.2024 Feb;17:105519

• 26. [IF=6.1] Shenke Bie et al."The profiles of free, esterified and insoluble-bound phenolics in peach juice after high pressure homogenization and evaluation of their antioxidant capacities, cytoprotective effect, and inhibitory effects on α-glucosidase and dipeptidyl

• 25. [IF=6.5] Feng Zhou et al."Integrated metabolomics and transcriptomic analysis reveals metabolic changes of flavor compounds of Camellia assamica host plant after parasitized by Viscum articulatum."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2023 Dec;205:108157

• 24. [IF=6.8] Huan Yu et al."Improving red pitaya fruit quality by nano-selenium biofortification to enhance phenylpropanoid and betalain biosynthesis."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2023 Nov;267:115653

• 23. [IF=3.5] Xiaojing Jing et al."Physiological, Photosynthetic, and Transcriptomics Insights into the Influence of Shading on Leafy Sweet Potato."Genes.2023 Dec;14(12):2112

• 22. [IF=6] Zeru Xu et al."Targeted screening of baicalein inhibitor with controlling lipid and protein oxidation for quality preservation of grass carp fillets."LWT-FOOD SCIENCE AND TECHNOLOGY.2023 Nov;:115526

• 21. [IF=8.8] Menglin Han et al."Exploring the interaction mechanism of chlorogenic acid and myoglobin: Insights from structure and molecular dynamics simulation."FOOD CHEMISTRY.2024 Apr;438:138053

• 20. [IF=3.1] Chongwang Ran et al."Hugan Buzure Granule Alleviates Acute Kidney Injury in Mice by Inhibiting NLRP3/Caspase-1 Pathway and TLR4/NF-κB Pathway."Frontiers in Bioscience-Landmark.2023 Nov;28(11):313

• 19. [IF=3.9] Xuanming Zhang et al."Active compounds from Calendula officinalis flowers act via PI3K and ERK signaling pathways to offer neuroprotective effects against Parkinson's disease."Food Science & Nutrition.2023 Oct;:

• 18. [IF=4.5] Zhongjing Zhou et al."Determination of Phenolic Acids Using Ultra-High-Performance Liquid Chromatography Coupled with Triple Quadrupole (UHPLC-QqQ) in Fruiting Bodies of Sanghuangporus baumii (Pilát) L.W. Zhou and Y.C. Dai."Plants-Basel.2023 Jan;12(20):356

• 17. [IF=4.6] Haodong Li et al."Active Components of Leontopodium alpinum Callus Culture Extract for Blue Light Damage in Human Foreskin Fibroblasts."MOLECULES.2023 Jan;28(21):7319

• 16. [IF=5.4] Yanqiu Sun et al."Network pharmacology integrated with experimental validation revealed the mechanism of Fengshi Gutong Capsule in the treatment of osteoarthritis."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;:117261

• 15. [IF=4.5] Bei Wu et al."Study on the Key Autotoxic Substances of Alfalfa and Their Effects."Plants-Basel.10.3390/plants12183263

• 14. [IF=5.2] Shufang Wu et al."An Exploration of Dynamic Changes in the Mulberry Growth Process Based on UPLC-Q-Orbitrap-MS, HS-SPME-GC-MS, and HS-GC-IMS."Foods.10.3390/foods12183335

• 13. [IF=5.4] Fanke Zeng et al."Distribution profiles of phenolic compounds in a cultivar of wampee (Clausena lansium (Lour.) Skeels) fruits and in vitro anti-inflammatory activity."JOURNAL OF ETHNOPHARMACOLOGY.10.1016/j.jep.2023.117168

• 12. [IF=6] Tian Li et al."Investigation of microbial succession and volatile compounds dynamics during the fermentation of traditional cereal vinegar in Xinjiang."LWT-FOOD SCIENCE AND TECHNOLOGY.10.1016/j.lwt.2023.115258

• 11. [IF=6.1] Xue Zhang et al."Identification strategy of Fructus Gardeniae and its adulterant based on UHPLC/Q-orbitrap-MS and UHPLC-QTRAP-MS/MS combined with PLS regression model."TALANTA.10.1016/j.talanta.2023.125136

• 10. [IF=7] Caijun Ren et al."Antioxidant Polyphenols from Lespedeza bicolor Turcz. Honey: Anti-Inflammatory Effects on Lipopolysaccharide-Treated RAW 264.7 Macrophages."Antioxidants.10.3390/antiox12101809

• 9. [IF=15.1] Hai Chen et al."Facile approach to fabricate stable multi-chamber colloid particles for compartmentalized encapsulation and reaction control of incompatible molecules."CHEMICAL ENGINEERING JOURNAL.10.1016/j.cej.2023.146029

• 8. [IF=5.2] Yujie Xie et al."Camellia oleifera seeds cake: Polyphenol profile and in vitro antioxidant activities as determined by different harvest periods."Food Bioscience.2023 Oct;55:103081

• 7. [IF=8.8] Yue Hu et al."Isolation, identification, and synergistic mechanism of a novel antimicrobial peptide and phenolic compound from fermented walnut meal and their application in Rosa roxbughii Tratt spoilage fungus."FOOD CHEMISTRY.2023 Aug;:137333

• 6. [IF=5.4] Mingxiang Xie et al."Molecular mechanism of PSORI-CM01 for psoriasis by regulating the inflammatory cytokines network."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;318:116935

• 5. [IF=6.1] Yuhan Sun et al."In Vitro and In Vivo Evaluation of Chlorogenic Acid-Encapsulated Lignin on Patulin Adsorption and Alleviation of Patulin-Induced Colonic Damage."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;71(29):11217–11227

• 4. [IF=7] Xuechun Zhang et al."Chemical Constituents, Antioxidant, and α-Glucosidase Inhibitory Activities of Different Fermented Gynostemma Pentaphyllum Leaves and Untargeted Metabolomic Measurement of the Metabolite Variation."Antioxidants.2023 Aug;12(8):1505

• 3. [IF=8.8] Siying Zhang et al."Sustained release of chlorogenic acid by co-encapsulation of sodium alginate binding to the Northern pike (Esox Lucius) liver ferritin."FOOD CHEMISTRY.2023 Dec;429:136924

• 2. [IF=8.8] Yuming Wei et al."Metabolomics analysis reveals the mechanism underlying the improvement in the color and taste of yellow tea after optimized yellowing."FOOD CHEMISTRY.2023 Jul;:136785

• 1. [IF=10.7] Hong Hu et al."Effect of different hydrocolloids on the physicochemical, printing, and digestion properties of 3D printed purple sweet potato."FOOD HYDROCOLLOIDS.2023 Nov;144:109058

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *