商品分類

瀏覽歷史

B20570	黃芩苷
源葉	分析標準品,HPLC≥98%

英文名：
Baicalin

別名：
黃芩甙，貝加靈

CAS號：
21967-41-9

分子式：
C₂₁H₁₈O₁₁

分子量：
446.37

MDL：
MFCD00134418

核磁/質譜：

品牌	貨號	產品規(guī)格	價格(RMB)	庫存（上海）	北京	武漢	南京	計量單位	加入購物車...
源葉	B20570-20mg	分析標準品,HPLC≥98%	￥90.00元	>10	-	2	>10	EA	加入購物車
源葉	B20570-100mg	分析標準品,HPLC≥98%	￥350.00元	>10	-	1	1	EA	加入購物車
源葉	B20570-200mg	分析標準品,HPLC≥98%	￥600.00元	>10	2	-	2	EA	加入購物車
源葉	B20570-1g	分析標準品,HPLC≥98%	￥1980.00元	>10	2	-	-	EA	加入購物車
源葉	B20570-1.7g	分析標準品,HPLC≥98%	￥3200.00元	>10	-	-	-	EA	加入購物車

大包裝詢價

提交您的電話號碼并同意《個人信息授權與保護申明》，到貨后將短信提示。
提交

產品介紹

參考文獻(175篇)

質檢證書(COA)

摩爾濃度計算器

相關產品

介紹：
Baicalin 作為一種類黃酮糖苷，是一種變構肉堿棕櫚酰轉移酶1 (CPT1)是激活劑。Baicalin 降低 NF-KB表達。

熔點： 202-205°C

沸點： 836.6 °C at 760 mmHg

比旋光度： -85°(C=1, DMSO)

外觀：淡黃色結晶粉末

溶解性： DMSO : ≥ 100 mg/mL (224.03 mM)

H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic)

儲存條件： 2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

175. [4.9] Zhongda Cao et al."Baicalin Inhibits FIPV Infection In Vitro by Modulating the PI3K-AKT Pathway and Apoptosis Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(18):9930

174. [7.7] Zhenjiang Zheng et al."Growth inhibition of pancreatic cancer by targeted delivery of gemcitabine via fucoidan-coated pH-sensitive liposomes."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Oct;277:134517

173. [2.7] Siqi Zhu et al."Baicalin attenuated oxidative stress and inflammation in ethylene glycol-induced urolithiasis in adult male SD rats."TISSUE & CELL.2024 Jun;:102453

172. [6.9] You Yi-ping et al."Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages."ACTA PHARMACOLOGICA SINICA.2024 Sep;:1-18

171. [4.8] Yongqiang Wen et al."Uncovering the protective mechanism of baicalin in treatment of fatty liver based on network pharmacology and cell model of NAFLD."INTERNATIONAL IMMUNOPHARMACOLOGY.2024 Nov;141:112954

170. [6.2] Jingzheng Li et al."Baicalin ameliorates heat stress-induced hepatic injury and intestinal microecology dysbiosis in late gestational mice."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Sep;283:116832

169. [7.2] Li Huang et al."Development of cantharidin/baicalin co-delivery system based on mitochondrial targeting strategy for enhanced hepatocellular carcinoma therapy."Applied Materials Today.2024 Oct;40:102374

168. [13] Yujie Fan et al."Coordination-Driven Nanomedicine Mitigates One-Lung Ventilation-Induced Lung Injury via Radicals Scavenging and Cell Pyroptosis Inhibition."Small.2024 Aug;:2401056

167. [4.1] Liu Meiqi et al."A multidimensional strategy for uncovering comprehensive quality markers of Scutellariae Radix based on UPLC-Q-TOF-MS analysis, artificial neural network, network pharmacology analysis, and molecular simulation."Frontiers in Plant Science

166. [6.7] Xianli Xu et al."Bu-Shen-Ning-Xin decoction ameliorates premature ovarian insufficiency by suppressing oxidative stress through rno_circRNA_012284/rno_miR-760-3p/HBEGF pathway."PHYTOMEDICINE.2024 Jul;:155920

165. [4.3] Hujun Du et al."Exploring the Underlying Mechanisms of Qingxing Granules Treating H1N1 Influenza Based on Network Pharmacology and Experimental Validation."Pharmaceuticals.2024 Jun;17(6):731

164. [IF=5.4] Dan Yang et al."Study on the Effect of Pharmaceutical Excipient PEG400 on the Pharmacokinetics of Baicalin in Cells Based on MRP2, MRP3, and BCRP Efflux Transporters."Pharmaceutics".2024 Jun;16(6):731

163. [IF=5.4] Rui Guo et al."Tanreqing injection inhibits influenza virus replication by promoting the fusion of autophagosomes with lysosomes: An integrated pharmacological study."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118159

162. [IF=7.5] Yanfang Zheng et al."Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin’s neuroprotective action against diabetes-induced cognitive impairment."BIOMEDICINE & PHARMACOTHERAPY".2024 May;174:116579

161. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038

160. [IF=3.4] Yanhua Jiang et al."Network pharmacology combined with lipidomics to reveal the regulatory effects and mechanisms of Kangzao granules in the hypothalamus of rats with central precocious puberty."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS".2024 May;

159. [IF=4.9] Huang Hefei et al."Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome."Chinese Medicine".2024 Dec;19(1):1-17

158. [IF=5.6] Heng Sun et al."Molecular-Scale Investigations Reveal the Effect of Natural Polyphenols on BAX/Bcl-2 Interactions."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES".2024 Jan;25(5):2474

157. [IF=5.6] Haipeng Feng et al."Baicalin Protects Broilers against Avian Coronavirus Infection via Regulating Respiratory Tract Microbiota and Amino Acid Metabolism."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES".2024 Jan;25(4):2109

156. [IF=7.9] Yanqin Luo et al."Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota."PHYTOMEDICINE".2024 May;:155706

155. [IF=5.2] Zhixia Wang et al."A carrier-free organometallic hydrogel originated from natural baicalin and Zn2+ with antibacterial and antioxidant efficacy."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2023 Dec;679:132585

154. [IF=5.4] Bo-Han Wang et al."Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway."JOURNAL OF ETHNOPHARMACOLOGY.10.1016/j.jep.2023.117203

153. [IF=0.7] Xianyong Li et al."Baicalin Promotes Apoptosis of Human Medullary Breast Cancer via the ERK/p38 MAPK Pathway."Pharmacognosy Magazine.;():

152. [IF=3] Weiwei Dai et al."Baicalin alleviates oxygen–glucose deprivation/reoxygenation-induced SK-N-SH cell injury via the regulation of miR-556-3p/ACSL4 pathway."Chemical Biology & Drug Design.2024 Jan;103(2):e14455

151. [IF=5] Ren Yanying et al."Quercetin: a promising virulence inhibitor of Pseudomonas aeruginosa LasB in vitro."APPLIED MICROBIOLOGY AND BIOTECHNOLOGY.2024 Dec;108(1):1-20

150. [IF=1.8] Yue Qian et al."Si Miao San relieves hyperuricemia by regulating intestinal flora."BIOMEDICAL CHROMATOGRAPHY.2023 Dec;:e5807

149. [IF=2.9] Qi Ying et al."Sanhuang Xiexin Decoction Ameliorates TNBC By Modulating JAK2-STAT3 and Lipid Metabolism."Chinese Journal of Integrative Medicine.2023 Nov;:1-10

148. [IF=5.4] Liangxin Zhao et al."UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;:117318

147. [IF=3.3] Li Li et al."Baicalin promotes antiviral IFNs production and alleviates type I IFN-induced neutrophil inflammation."Journal of Natural Medicines.2023 Jul;:1-11

146. [IF=4.3] Bao-Fei Yan et al."Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway."WORLD JOURNAL OF GASTROENTEROLOGY.2023 Aug 21; 29(31): 4744–4762

145. [IF=6] Shuai Yan et al."Baicalin Suppresses Colorectal Cancer Cell Proliferation, Potentially via ARRDC4: Bioinformatics and Experimental analysis."Arabian Journal of Chemistry.2023 Jul;:105141

144. [IF=5.2] Guo Huanyu et al."The combined effect of a novel formula of herbal extracts on bacterial infection and immune response in Micropterus salmoides."Frontiers in Microbiology.2023 Jun;14:

143. [IF=5.4] Miaomiao Liu et al."Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116745

142. [IF=7.5] Jingwen Yuan et al."Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis."BIOMEDICINE & PHARMACOTHERAPY.2023 Aug;164:114986

141. [IF=3.976] Su Jianqing et al."Pharmacokinetic Studies of Hyperoside-2-hydroxypropyl-β-cyclodextrin Inclusion Complex and It Ameliorated DSS-Induced Colitis in Mice."BIOSCIENCE REPORTS.2023 May;:

140. [IF=4.221] Xixi Fan et al."Baicalin inhibits the replication of the hepatitis B virus by targeting TRIM25."Journal of Traditional and Complementary Medicine.2023 May;:

139. [IF=6.388] Jialing Sun et al."Baicalin inhibits hepatocellular carcinoma cell growth and metastasis by suppressing ROCK1 signaling."PHYTOTHERAPY RESEARCH.2023 May;:

138. [IF=9.965] Junxiao Zhu et al."Are all poorly soluble drugs dissolved in deep eutectic solvents true solutions?."JOURNAL OF COLLOID AND INTERFACE SCIENCE.2023 Sep;645:813

137. [IF=2.139] Y Zhang et al."Baicalin alleviates silica-induced lung inflammation and fibrosis by inhibiting TLR4/NF-?B pathway in rats."PHYSIOLOGICAL RESEARCH.2023 Apr 30;72(2):221-233

136. [IF=2.742] Li Mengyuan et al."Baicalin can enhance odonto/osteogenic differentiation of inflammatory dental pulp stem cells by inhibiting the NF-κB and β-catenin/Wnt signaling pathways."MOLECULAR BIOLOGY REPORTS.2023 Apr;:1-12

135. [9.429] Su Wenting et al."An intravitreal-injectable hydrogel depot doped borneol-decorated dual-drug-coloaded microemulsions for long-lasting retina delivery and synergistic therapy of wAMD."JOURNAL OF NANOBIOTECHNOLOGY.2023 Dec;21(1):1-19

134. [3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683

133. [4.927] Bingyu Shen et al."Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways."MOLECULES.2023 Jan;28(4):1873

132. [7.419] Mengli Li et al."Baicalin mitigates hypertension-linked alterations in the intestinal lymphatic vasculature in part through preserving the functional barrier integrity of lymphatic endothelial cells."BIOMEDICINE & PHARMACOTHERAPY.2023 Apr;160:114418

131. [2.586] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid c

130. [4.831] Jing Sun et al."Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2023 Apr;2

129. [3.318] Hui Luo et al."Efficacy identification and active compounds screening of topically administration of Scutellaria Radix in oral ulcer."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Dec;:123571

128. [5.195] Bao-Fei Yan et al."Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:115999

127. [6.525] Xingxing Dai et al."Diammonium Glycyrrhizinate-Based Micelles for Improving the Hepatoprotective Effect of Baicalin: Characterization and Biopharmaceutical Study."Pharmaceutics.2023 Jan;15(1):125

126. [5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919

125. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

124. [IF=5.195] Xin Deng et al."A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis."JOURNAL OF ETHNOPHARMACOLOGY.20

123. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

122. [IF=2.721] Haipeng Feng et al."Antiviral activity and underlying mechanisms of Baicalin against avian infectious bronchitis virus in vitro."AVIAN PATHOLOGY

121. [IF=5.988] Qihan Luo et al."Chang qing formula ameliorates colitis-associated colorectal cancer via suppressing IL-17/NF-κB/STAT3 pathway in mice as revealed by network pharmacology study."Frontiers in Pharmacology.2022; 13: 893231

120. [IF=6.212] Fei Huang et al."Discovery of conversion driven by β-glucuronidase from flavone glycoside to aglycone and application in identifying the raw Scutellariae Radix."Arabian Journal of Chemistry.2022 Aug;:104216

119. [IF=3.322] Dongjiu Zhao et al."Baicalin promotes antibacterial defenses by modulating mitochondrial function."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2022 Sep;621:130

118. [IF=5.195] Mengmeng Song et al."Homeostatic regulation of the aryl hydrocarbon receptor-cytochrome P450 1a axis by Scutellaria baicalensis-Coptis chinensis herb pair and its main constituents."JOURNAL OF ETHNOPHARMACOLOGY.2022 Jul;:115545

117. [IF=8.025] Ying Wang et al."Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation."INT

116. [IF=3.935] Yizhu Wang et al."Effects of Scutellaria baicalensis Georgi. on Intestinal Flora in Rats with Spleen Deficiency and Damp-heat."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114831

115. [IF=5.095] Liu Fengjie et al."Baicalin-loaded folic acid-modified albumin nanoparticles (FA-BSANPs/BA) induce autophagy in MCF-7 cells via ROS-mediated p38 MAPK and Akt/mTOR pathway."Cancer Nanotechnol. 2022 Dec;13(1):1-21

114. [IF=4.072] He Pang et al."Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways."J Bone Oncol. 2022 Apr;33:100415

113. [IF=3.205] Wanli Ji et al."Revealing therapeutic targets and mechanism of baicalin for anti-chronic gastritis using proteomic analysis of the gastric tissue."J Chromatogr B. 2022 Mar;:123214

112. [IF=2.193] Zhang Haibo et al.Systematic Study on a Quantitative Analysis of Multicomponents by Single Marker (QAMS) Method for Simultaneous Determination of Eight Constituents in Pneumonia Mixture by UPLC-MS/MS.J Anal Methods Chem. 2021;2021:8311588

111. [IF=4.36] Jiali Zhou et al.The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy.J Ethnopharmacol. 2022 Feb;284:114790

110. [IF=1.625] Hong-Jing Sun et al."Baicalin Alleviates Age-Related Macular Degeneration via miR-223/NLRP3-Regulated Pyroptosis."Pharmacology. 2020;105(1-2):28-38

109. [IF=1.851] Rui Li et al."Baicalin inhibits influenza virus A replication via activation of type?I IFN signaling by reducing miR?146a."Mol Med Rep. 2019 Dec;20(6):5041-5049

108. [IF=1.913] Zheng XP et al."Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin.."Bmc Nephrol. 2020 May;21(1):174-174

107. [IF=2.193] Xue Gen et al."Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA."J Anal Methods Chem. 2021;2021:9991363

106. [IF=2.193] Xu Tong et al."A Preferable Approach for the Quality Control of Xiaoer Chiqiao Qingre Granules Based on the Combination of Chromatographic Fingerprints and Chemometrics."J Anal Methods Chem. 2020;2020:6836981

105. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535

104. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

103. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788

102. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328

101. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002

100. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820

99. [IF=3.935] Chenglong Sun et al."A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi."J Pharmaceut Biomed. 2020 Feb;179:113014

98. [IF=4.162] Leyi Ma et al."Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway."Drug Des Dev Ther. 2021; 15: 3207–3221

97. [IF=4.225] Wu Dandan et al."Baicalin Protects Against Hypertension-Associated Intestinal Barrier Impairment in Part Through Enhanced Microbial Production of Short-Chain Fatty Acids."Front Pharmacol. 2019 Oct;0:1271

96. [IF=4.545] Xiangyan Wu et al."Qingda granules attenuate hypertensive cardiac remodeling and inflammation in spontaneously hypertensive rats."Biomed Pharmacother. 2020 Sep;129:110367

95. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625

94. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra

93. [IF=5.11] Xiaonan Liu et al."De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae."Acs Synth Biol. 2020;9(11):3042–3051

92. [IF=5.246] Sui Xinbing et al."Baicalin Induces Apoptosis and Suppresses the Cell Cycle Progression of Lung Cancer Cells Through Downregulating Akt/mTOR Signaling Pathway."Front Mol Biosci. 2021 Jan;0:323

91. [IF=5.279] Yanan Gao et al."Galactosylation of Monosaccharide Derivatives of Glycyrrhetinic Acid by UDP-Glycosyltransferase GmSGT2 from Glycine max."J Agr Food Chem. 2020;68(32):8580–8588

90. [IF=5.34] Shihao Yan et al."Network pharmacology-based identification of significant pathway for protection of Yinhuang granule in a mice model of metabolic-associated fatty liver disease."Phytomedicine. 2021 Oct;91:153666

89. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369

88. [IF=5.81] Zhenyu Fan et al."Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis."Front Pharmacol. 2021; 12: 628988

87. [IF=5.833] Zhou Zhidu et al."Ultra-sensitive amperometric determination of quercetin by using a glassy carbon electrode modified with a nanocomposite prepared from aminated graphene quantum dots, thiolated β-cyclodextrin and gold nanoparticles."Microchim Acta. 2020

86. [IF=5.875] Yumei Wu et al."Brain targeting of Baicalin and Salvianolic acid B combination by OX26 functionalized nanostructured lipid carriers."Int J Pharmaceut. 2019 Nov;571:118754

85. [IF=6.17] Liang Shi et al."Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation."Free Radical Bio Med. 2020 Nov;160:163

84. [IF=9.381] Ya Zhao et al."Polysaccharide from vinegar baked radix bupleuri as efficient solubilizer for water-insoluble drugs of Chinese medicine."Carbohyd Polym. 2020 Feb;229:115473

83. [IF=3.205] Xianhua Zhang et al."Pharmacokinetic study of representative anti-oxidative compounds from Denshen-Chuanxiong-Honghua following oral administration in rats."J Chromatogr B. 2017 May;1052:82

82. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56

81. [IF=3.845] Zhang Xianhua et al."Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds."Front Pharmacol. 2017 Jul;0:452

80. [IF=3.935] Yanqiu Gu et al."Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix."J Pharmaceut Biomed. 2019 Feb;164:550

79. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239

78. [IF=4.101] Hai-yan Zhu et al."Baicalin inhibits autophagy induced by influenza A virus H3N2."Antivir Res. 2015 Jan;113:62

77. [IF=4.96] Liang Shi et al."Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC."Biochem Pharmacol. 2018 Apr;150:9

76. [IF=6.057] Kai Sheng et al."Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin."Talanta. 2017 Mar;164:249

75. [IF=6.529] Liliqiang Ding et al."Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats."Biomed Pharmacother. 2019 Mar;111:325

74. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https://

73. Xu, Jun. "Improved approaches and strategies for analyzing decoctions of medicinal herbs." (2016).

72. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164

71. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https://doi.org/10.1002/clen.201300193

70. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https://doi.org/10.1016/j.jpba.2019.11

69. Shi, Liang, et al. "Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC." Biochemical pharmacology 150 (2018): 9-23.https://doi.org/10.1016/j.bcp.2018.01.026

68. Xue, Gen, et al. "Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA."?Journal of Analytical Methods in Chemistry?2021 (2021).https://doi.org/10.11

67. Sui, Xinbing, et al. "Baicalin induces apoptosis and suppresses the cell cycle progression of lung cancer cells through downregulating Akt/mTOR signaling pathway." Frontiers in Molecular Biosciences 7 (2021): 323.https://doi.org/10.3389/fmolb.2020.602282

66. Zhu, Hai-yan, et al. "Baicalin inhibits autophagy induced by influenza A virus H3N2." Antiviral research 113 (2015): 62-70.https://doi.org/10.1016/j.antiviral.2014.11.003

65. Shi, Liang, et al. "Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation." Free Radical Biology and Medicine 160 (2020): 163-177.https://doi.org/10.1016/j.freeradbiomed.2020.05.012

64. Wu, Dandan, et al. "Baicalin protects against hypertension-associated intestinal barrier impairment in part through enhanced microbial production of short-chain fatty acids." Frontiers in pharmacology 10 (2019): 1271.https://doi.org/10.3389/fphar.2019.0127

63. Ding, Liliqiang, et al. "Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats." Biomedicine & Pharmacotherapy 111 (2019): 325-330.https://doi.org/10.1016/j.biopha.2018.12.086

62. G. Qi, A. Liu, Z. Liu and Z. Bai, "A Novel HPLC Method for Determining Three Effective Components in Chinese Medicine 'Xiao' Erjiebiao Granules," 2012 International Conference on Biomedical Engineering and Biotechnology, 2012, pp. 16-20, doi: 10.1109/iCBEB

61. Sheng, Kai, et al. "Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin." Talanta 164 (2017): 249-256.https://doi.org/10.1016/j.talanta.2016.11.050

60. Sheng, Kai, et al. "Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin." Talanta 164 (2017): 249-256.https://doi.org/10.1016/j.talanta.2016.11.050

59. 劉萍,唐代,王旭,白云.黃芩苷對心肌缺血再灌注損傷的保護作用機制[J].中醫(yī)藥學報,2021,49(02):16-21.

58. 黃芳,孫亞寧,?？?馮丹丹,王志強.黃芩苷對低氧誘導的新生大鼠肺損傷的保護作用[J].中國藥理學與毒理學雜志,2020,34(10):736-742.

57. 唐君,杜楊,趙鳳嬌,崔勐,劉志強.電噴霧串聯質譜研究黃芩苷與谷胱甘肽的相互作用[J].應用化學,2021,38(03):331-342.

56. 林珊,陳達鑫,蔡巧燕,張鈴,陳靜雯,李金艷,彭軍,褚劍鋒.UPLC法測定清達顆粒和清眩降壓湯中黃芩苷的含量[J].福建中醫(yī)藥,2021,52(03):30-32.

55. 鄧遠雄,胡劍卓,佘成燁,李靜.高脂血癥大鼠灌胃黃連解毒湯后黃芩苷的藥代動力學研究[J].中南藥學,2020,18(12):1986-1991.

54. 李壯壯, 張靜, 趙紹哲,等. 指紋圖譜與化學計量學結合優(yōu)選柴胡桂枝顆粒水提工藝[J]. 中成藥, 2018, v.40(08):199-203.

53. 姜萬舟, 高平, 楊明德,等. 杏鮑菇乙醇提取物的抗氧化活性及成分分離鑒定[J]. 食品工業(yè)科技, 2015, 36(22):87-91.

52. 楊夢玲, 尤朋濤, 何麗珊,等. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動力學[J]. 中國中藥雜志, 2018, 43(18).

51. 陳智. 金銀花和黃芩不同煎煮方式化學成分變化及抗病毒作用比較[J]. 中華中醫(yī)藥雜志, 2019, v.34(10):129-133.

50. 張靜李壯壯杜寶香等. HPLC法同時測定柴胡桂枝湯中6種成分[J]. 中成藥 2018 040(010):2202-2205.

49. 李云靜, 張建逵, 趙玥,等. 黃芩藥材顏色及其有效成分的相關性[J]. 中國醫(yī)藥工業(yè)雜志, 2017(7).

48. 吳貴才, 趙丹, 曾青磊,等. 黃芩苷誘導人乳腺癌細胞株MCF-7凋亡的機制研究[J]. 中國醫(yī)藥科學, 2017, 7(005):14-18.

47. 楊潔, 李日嬋. 黃芩苷抑制H5N1禽流感病毒進入的機制研究[J]. 天然產物研究與開發(fā), 2016, v.28(02):98-102.

46. 范景輝, 趙玉梅, 張穎,等. 黃芩苷對糖尿病合并非酒精脂肪肝大鼠血脂和肝功能的影響觀察[J]. 中國現代醫(yī)生, 2020(9):29-31.

45. 吳峰淼,葉凱麗,劉曦.黃芩苷對大鼠膠原誘導性關節(jié)炎JAK/STAT3信號通路及Th17/Treg免疫平衡的影響[J].中國藥師,2020,23(02):246-251.

44. 何志堅, 勝海峰, 劉海云. 黃芩苷對大鼠放射性肺損傷的保護作用[J]. 實用癌癥雜志, 2018, v.33;No.199(10):5-8.

43. 馬雙, 宋鵬琰, 韓超,等. 黃芩苷對雙酚A致小鼠生殖損傷的保護作用[J]. 中國獸醫(yī)學報, 2018, 038(009):1753-1760.

42. 馬宗敏, 劉佳, 段緒紅,等. 黃芩苷發(fā)酵轉化成黃芩素和千層紙素A的黃芩內生真菌的篩選及鑒定[J]. 中國實驗方劑學雜志, 2019(9):166-171.

41. 徐治中,竺平,周寄文,楊柏霖.黃芩苷促使細胞G2/M阻滯抑制錯配修復基因缺失的結直腸癌裸鼠原位移植瘤生長[J].中藥藥理與臨床,2017,33(02):24-28.

40. 何谷良, 袁娉, 黃家望,等. 黃芩苷體外對耐甲氧西林金黃色葡萄球菌活性影響的研究[J]. 時珍國醫(yī)國藥, 2019(4).

39. 郭凈潔, 王崇, 張維甲,等. 黃芩素與黃芩苷聯合用藥對口腔鱗癌細胞增殖,遷移的影響[J]. 口腔醫(yī)學, 2020, 040(005):393-398.

38. 頓佳穎, 李佳佳, 鄭鵬,等. 黃芩湯傳統湯劑與配方顆粒中3種有效成分的比較研究[J]. 中醫(yī)藥導報, 2019, 25(05):78-81+89.

37. 程燕, 曲紹風, 李福偉,等. 黃芩中4種黃酮類化合物的亞臨界水提取研究[J]. 山東科學, 2013(03):11-14.

36. 山光強, 陳志剛, 許廣人,等. 金櫻子總黃酮的含量測定及酶提工藝優(yōu)化[J]. 中國畜牧獸醫(yī), 2016, 43(012):3156-3162.

35. 何原, 黃石安, 陳燦,等. 進口與國產黃芩苷對低氧性肺動脈平滑肌細胞增殖影響的比較[J]. 廣東醫(yī)學, 2016, 37(010):1433-1436.

34. 陳海君, 馬尚智, 江敏,等. 超濾親和-液質聯用和分子對接技術篩選毛菊苣根中α-葡萄糖苷酶抑制劑[J]. 中草藥, 2019, 50(02):85-92.

33. 宗春燕, 蘇學軍, 梁雅娟. 超聲浸漬法提取木蝴蝶中總黃酮的工藝研究[J]. 化學工程師, 2019, 33(02):18-20.

32. 李蒙蒙,田小杏,馬麗娟,蒲曉輝,袁琦,宗蘭蘭,徐穎峰.薄層色譜法鑒別三黃片中的有效成分[J].河南大學學報(醫(yī)學版),2016,35(02):81-84+109.

31. 譚麗麗,楊向方,李燕廣,張國徽.缺血預處理聯合黃芩苷預處理對大鼠腦缺血再灌注半暗帶細胞凋亡及Bcl-2/Bax比值的影響[J].中西醫(yī)結合心腦血管病雜志,2014,12(02):220-221.

30. 董浩浩, 李從舉. 離子交換纖維吸附黃芩苷的動力學與熱力學研究[J]. 西南師范大學學報(自然科學版), 2014, 000(001):7-14.

29. 李納,李姣嬌,范蕾,陳章寶.用山銀花與金銀花制備雙黃連口服液質量比較研究[J].西北藥學雜志,2018,33(01):6-10.

28. 尹麗, 張瀟菡, 馬麗娟,等. 牛黃解毒片的顯微鑒別及薄層鑒別[J]. 河南大學學報(醫(yī)學版), 2016(2):85-88.

27. 郭允, 陳永超, 李曉花,等. 牛黃解毒片中6種指標成分的含量測定[J]. 沈陽藥科大學學報, 2016(6):454-458.

26. 林珊, 張鈴, 蔡巧燕,等. 清眩降壓湯對離體大鼠胸主動脈的舒張作用及黃芩苷成分分析[J]. 福建中醫(yī)藥, 2018, 049(001):34-36.

25. 李玲云,王云,劉夢嬌,張雪,李曉慶,戴業(yè)佳,麻印蓮,張村.梔子金花丸化學成分的UPLC-Q-TOF-MS/MS快速鑒定與分析[J].中國實驗方劑學雜志,2017,23(14):1-11.

24. 楊爽, 何妍茜, 楊潔,等. 感冒軟膠囊質量標準提高的研究[J]. 時珍國醫(yī)國藥, 2013, 24(008):1930-1932.

23. 余歡歡, 黃啟迪, 顏美秋,等. 孕康口服液3種成分測定及HPLC指紋圖譜建立[J]. 中成藥, 2020, v.42(03):46-51.

22. 劉媛媛, 劉陶, 吳玉梅,等. 基于雌激素受體調節(jié)Nrf2-ARE通路的黃芩中抗氧化成分的篩選[J]. 中國藥理學通報, 2019, 035(006):822-827.

21. 袁杰, 李錟, 周利,等. 基于超高效液相色譜法和色差儀法的黃芩藥材質量評價[J]. 世界中醫(yī)藥, 2019.

20. 商利娜, 王亞靜, 趙鑫,等. 基于譜-效關系探究黃芩抑制白色念珠菌的質量標志物[J]. 中成藥, 2020, 042(005):1357-1361.

19. 柴沖沖,曹妍,毛民,王靖越,劉娜,李欣欣,張凱,陳東玲,魏龍吟,尹怡慧,李飛.基于電子舌技術評價黃芩酒炙前后滋味變化及其在黃芩飲片鑒別中的應用研究[J].中國中藥雜志,2020,45(11):2552-2559.

18. 劉艷, 楊炳友, 孫艷,等. 基于活性和Plackett-Burnman聯合Box-Behnken設計的復方梔子金花提取工藝優(yōu)化[J]. 中華中醫(yī)藥雜志, 2019, 34(04):69-73.

17. 張建逵,李云靜,孫智,王冰,康廷國.基于斷面色澤測定的條芩飲片分級研究[J].中國中藥雜志,2017,42(21):4115-4119.

16. 任永申, 鄧鑫, 雷蕾,等. 基于抑菌效應成分指紋譜的黃芩質量評價研究[J]. 藥學學報, 2019, 054(012):2155-2161.

15. 李淑嬌, 王宇卿. 基于HPLC-Q-TOF/MS法的黃芩血清藥物化學分析[J]. 中成藥, 2019, 41(03):117-122.

14. 侯廣玉李孟全趙鵬程王一成朱立雙杜書迪.咳爾康顆粒對肺腺癌細胞A549的體外抗腫瘤作用[J].醫(yī)藥導報 2019 38(01):27-32.

13. 陳慧潔楊亞楠丁輝等. 養(yǎng)陰利咽半生制劑袋泡茶的制備及優(yōu)化[J]. 天津中醫(yī)藥大學學報 2019 38(01):78-83.

12. 萬鵬趙瑞芝胡巧紅. 中藥多糖對黃芩苷的溶解度及其藥動學的影響[J]. 廣東藥學院學報 2017(4).

11. 秦書芝李鳳張瑤等. 不同軟化處理方法對黃芩飲片中黃芩苷含量影響[J]. 海峽藥學 2017(10):30-31.

10. 柴沖沖毛民袁金鳳等. 不同方法軟化切制后的黃芩飲片顏色與5種黃酮類成分含量的相關性研究[J]. 中國中藥雜志 2019.

9. 楊強蒲曉輝李曉花. 一清膠囊中7種指標成分的測定[J]. 華西藥學雜志 2017(3).

8. 范匯森閆秋瑩張海彬等. UPLC-MS/MS法測定大鼠血漿中紫草氰苷格列風內酯濃度簡[J]. 南京中醫(yī)藥大學學報 2018(1):91-95.

7. 康寧芳李梅胡賀佳肖紅琴劉利琴李銀李月婷王愛民王永林張昀何峰鞏仔鵬.UPLC-MS/MS同時測定舒肝寧注射液在大鼠血漿中4種活性成分的含量及其藥代動力學研究[J].中國中藥雜志 2020 45(11):2626-2633.

6. 劉阿靜齊廣才劉珍葉等. RP—HPLC法測定防風通圣丸中芍藥苷梔子苷黃芩苷和連翹苷的含量[J]. 西北藥學雜志 2012 27(5):415-415.

5. 郝乘儀張慧鋒楊明慧. RP-HPLC法同時測定小兒肺熱咳喘顆粒中兩種主要活性成分的含量[J]. 吉林醫(yī)藥學院學報 2017(1).

4. 李曉花郭允李佳袁琦蒲曉輝王高峰.RP-HPLC法同時測定三黃片中7種指標成分的含量[J].沈陽藥科大學學報 2016 33(08):637-642.

3. 張宏梅昌盛崔佰吉等. HPLC法同時測定茵膽平肝膠囊中6種成分的含量[J]. 中國藥房 2017年28卷9期 1239-1242頁 ISTIC PKU CA 2017 28(9):1239-1242.

2. 吳宇鋒陳靈哲林忠. HPLC法同時測定3種煎法下防風通圣方中的黃芩苷和梔子苷含量[J]. 上海醫(yī)藥 2018 v.39;No.493(01):64-67.

1. 王東超魏穎高佳琪孫文秦靈靈蘭衛(wèi) 石浩霞李博徐暾海劉銅華.HPLC同時測定糖痹康顆粒中黃芩苷、漢黃芩苷、黃芩素、漢黃芩素的含量[J].吉林中醫(yī)藥 2017 37(05):513-517.