• 介紹：

   Baicalein (5,6,7-Trihydroxyflavone) 是黃嘌呤氧化酶抑制劑，其 IC₅₀ 值為 3.12 μM。

• 熔點： 256-271°C

• 沸點： 575.9°C at 760 mmHg

• 比旋光度： -14°(水)；-139°(吡啶)

• 外觀： 黃色粉末

• 溶解性： DMSO  :  50  mg/mL  (185.02  mM;  Need  ultrasonic)

• 敏感性： 對光和熱敏感

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 113. [IF=5.2] Qiuyan Jiang et al."Baicalein ameliorates lipid accumulation in HepG2 cells via the pregnane X receptor signaling pathway."Food Bioscience".2024 Aug;60:104482

• 112. [IF=5.4] Dan Yang et al."Study on the Effect of Pharmaceutical Excipient PEG400 on the Pharmacokinetics of Baicalin in Cells Based on MRP2, MRP3, and BCRP Efflux Transporters."Pharmaceutics".2024 Jun;16(6):731

• 111. [IF=5.6] Han Yu et al."Functional Identification of HhUGT74AG11—A Key Glycosyltransferase Involved in Biosynthesis of Oleanane-Type Saponins in Hedera helix."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES".2024 Jan;25(7):4067

• 110. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038

• 109. [IF=6.6] Lingling Tang et al."Cleaner production of baicalein by novel high-temperature-little-acid hydrolysis of baicalin."Green Chemistry Letters and Reviews.10.1080/17518253.2024.2319698

• 108. [IF=7.9] Yanqin Luo et al."Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota."PHYTOMEDICINE".2024 May;:155706

• 107. [IF=5.4] Botong Li et al."Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;322:117578

• 106. [IF=5.6] Lei Xie et al."Synthesis of Crocin I and Crocin II by Multigene Stacking in Nicotiana benthamiana."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.10.3390/ijms241814139

• 105. [IF=5.4] Wenqiang Yao et al."Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;321:117536

• 104. [IF=2.8] Qingmei Gong et al."Baicalein promotes the microglia M2 polarization and suppresses apoptosis by targeting HMOX1/PDE4D to alleviate Alzheimer’s disease."IMMUNOBIOLOGY.2023 Nov;:152761

• 103. [IF=6] Zeru Xu et al."Targeted screening of baicalein inhibitor with controlling lipid and protein oxidation for quality preservation of grass carp fillets."LWT-FOOD SCIENCE AND TECHNOLOGY.2023 Nov;:115526

• 102. [IF=4.3] Bao-Fei Yan et al."Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway."WORLD JOURNAL OF GASTROENTEROLOGY.2023 Aug 21; 29(31): 4744–4762

• 101. [IF=1.7] Zhouyi Zhang et al."Revealing the differences in phenolics in different parts of Taraxacum mongolicum using UPLC-MS/MS."Phytochemistry Letters.2023 Aug;56:13

• 100. [IF=5.1] Meiling Yu et al."Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation."CHEMICO-BIOLOGICAL INTERACTIONS.2023 Sep;382:110607

• 99. [IF=5.2] Guo Huanyu et al."The combined effect of a novel formula of herbal extracts on bacterial infection and immune response in Micropterus salmoides."Frontiers in Microbiology.2023 Jun;14:

• 98. [IF=5.4] Miaomiao Liu et al."Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116745

• 97. [IF=1.967] ke Zunli et al."Physicochemical characteristics, polyphenols and antioxidant activities of Dimocarpus longan grown in different geographical locations."ANALYTICAL SCIENCES.2023 Apr;:1-8

• 96. [IF=3.842] Qiao Yinggu et al."Boldine promotes stemness of human urine-derived stem cells by activating the Wnt/β-catenin signaling pathway."MOLECULAR AND CELLULAR BIOCHEMISTRY.2023 Apr;:1-12

• 95. [IF=6.656] Siqi Liu et al."Screening quality makers (Q-makers) of Xiaoer Chaige Tuire Oral Liquid by in vitro sequential metabolism and in vivo biopharmaceutical analysis."PHYTOMEDICINE.2023 Apr;:154844

• 94. [IF=12.779] Haiyu Xu et al."Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19."PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.2023 Apr;120(18):e2301775120

• 93. [1.555] Huang Zhen et al."Screening Antibacterial Constituents of Scutellaria Radix Based on Spectrum–Effect Relationships Between HPLC Fingerprints and the Inhibition of Oral Bacteria."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2023 Mar;:

• 92. [1.467] Wen-Xia Pi et al."Simultaneous quantification of multiple active components of the ginkgo ketoester tablet when combined with donepezil in four biological matrices from an Alzheimer’s animal model: Evaluation of drug distribution patterns in?vivo."JOURNA

• 91. [3.682] Yujia Liu et al."Dual-responsive antibiotic and baicalein co-delivery nanoparticles with enhanced synergistic antibacterial activity."JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION.

• 90. [6.208] Na Li et al."STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(3):2987

• 89. [2.586] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid c

• 88. [4.831] Jing Sun et al."Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2023 Apr;2

• 87. [3.318] Hui Luo et al."Efficacy identification and active compounds screening of topically administration of Scutellaria Radix in oral ulcer."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Dec;:123571

• 86. [5.195] Bao-Fei Yan et al."Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:115999

• 85. [5.195] Shou-Jia Wang et al."Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:116053

• 84. [7.291] Liu Xiaojuan et al."Genome-wide analysis of cytochrome P450 genes in Citrus clementina and characterization of a CYP gene encoding flavonoid 3'-hydroxylase."Horticulture Research.2022 Dec;:

• 83. [8.431] Dan Huang et al."Scavenging of reactive oxygen species effectively reduces Pseudomonas aeruginosa biofilms through disrupting policing."ENVIRONMENTAL RESEARCH.2023 Mar;220:115182

• 82. [5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919

• 81. [6.269] Mengyu Cai et al."Nutritional supplements formulated to prevent cognitive impairment in animals."Current Research in Food Science.2022 Jan;5:2294

• 80. [IF=5.195] Weicong Chen et al."Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts."JOURNAL OF ETHNOPHARMACOLOGY.2022 Oct;:115825

• 79. [IF=5.195] Zhen Huang et al."Efficacy confirmation of Scutellaria baicalensis Georgi in the treatment of periodontitis via topical administration and active ingredients screening."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jan;300:115699

• 78. [IF=5.195] Xin Deng et al."A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis."JOURNAL OF ETHNOPHARMACOLOGY.20

• 77. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

• 76. [IF=7.419] Yule Wang et al."Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish."BIOMEDICINE & PHARMACOTHERAPY.2022 Nov;155:113744

• 75. [IF=6.212] Fei Huang et al."Discovery of conversion driven by β-glucuronidase from flavone glycoside to aglycone and application in identifying the raw Scutellariae Radix."Arabian Journal of Chemistry.2022 Aug;:104216

• 74. [IF=8.025] Ying Wang et al."Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation."INT

• 73. [IF=9.473] Yujing Wang et al."Scutellarein Attenuates Atopic Dermatitis by Selectively Inhibiting Transient Receptor Potential Vanilloid 3."BRITISH JOURNAL OF PHARMACOLOGY

• 72. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426

• 71. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155

• 70. [IF=5.811] 

• 69. [IF=3.935] Yizhu Wang et al."Effects of Scutellaria baicalensis Georgi. on Intestinal Flora in Rats with Spleen Deficiency and Damp-heat."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114831

• 68. [IF=4.412] Jingjing Liao et al."Heterologous Biosynthesis of Health-Promoting Baicalein in Lycopersicon esculentum."MOLECULES. 2022 Jan;27(10):3086

• 67. [IF=4.821] Tian Quan et al."Effective extraction methods based on hydrophobic deep eutectic solvent coupled with functional molecularly imprinted polymers: Application on quercetagetin extraction from natural medicine and blood."Microchem J. 2022 Mar;174:107076

• 66. [IF=6.529] Fanying Meng et al."Virtual screening and in vitro experimental verification of LuxS inhibitors from natural products for Lactobacillus reuteri."Biomed Pharmacother. 2022 Mar;147:112521

• 65. [IF=7.514] Jinmiao Sun et al."Chitosan binding to a novel alfalfa phytoferritin nanocage loaded with baicalein: Simulated digestion and absorption evaluation."Food Chem. 2022 Aug;386:132716

• 64. [IF=3.41] Zhi-dan Gao et al."Mechanistic insights into the amelioration effects of lipopolysaccharide-induced acute lung injury by baicalein: An integrated systems pharmacology study and experimental validation."Pulm Pharmacol Ther. 2022 Mar;:102121

• 63. [IF=2.193] Zhang Haibo et al.Systematic Study on a Quantitative Analysis of Multicomponents by Single Marker (QAMS) Method for Simultaneous Determination of Eight Constituents in Pneumonia Mixture by UPLC-MS/MS.J Anal Methods Chem. 2021;2021:8311588

• 62. [IF=4.36] Jiali Zhou et al.The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy.J Ethnopharmacol. 2022 Feb;284:114790

• 61. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535

• 60. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 59. [IF=3.004] Chun Chen et al."Comparative two-dimensional GPC3 overexpressing SK-Hep1 cell membrane chromatography /C18/ time-of-flight mass spectrometry for screening selective GPC3 inhibitor components from Scutellariae Radix."J Chromatogr B. 2021 Jan;1163:122492

• 58. [IF=3.263] Zongchun Yang et al."Baicalein improves glucose metabolism in insulin resistant HepG2 cells."Eur J Pharmacol. 2019 Jul;854:187

• 57. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788

• 56. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820

• 55. [IF=3.935] Chenglong Sun et al."A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi."J Pharmaceut Biomed. 2020 Feb;179:113014

• 54. [IF=4.35] Wanpei Tang et al."Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus)."Foods. 2021 Jun;10(6):1183

• 53. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625

• 52. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra

• 51. [IF=5.11] Xiaonan Liu et al."De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae."Acs Synth Biol. 2020;9(11):3042–3051

• 50. [IF=5.279] Yanan Gao et al."Galactosylation of Monosaccharide Derivatives of Glycyrrhetinic Acid by UDP-Glycosyltransferase GmSGT2 from Glycine max."J Agr Food Chem. 2020;68(32):8580–8588

• 49. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro

• 48. [IF=5.875] Guangjiao You et al."Preparation, optimization, characterization and in vitro release of baicalein-solubilizing glycyrrhizic acid nano-micelles."Int J Pharmaceut. 2021 May;601:120546

• 47. [IF=3.597] Jingying Qiu et al."Assessment of a bifendate derivative bearing a 6,7-dihydro-dibenzo[c,e]azepine scaffold as a potential anti-metastatic agent."Medchemcomm. 2018 Nov;9(11):1826-1830

• 46. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56

• 45. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239

• 44. [IF=4.96] Liang Shi et al."Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC."Biochem Pharmacol. 2018 Apr;150:9

• 43. [IF=5.875] Qiuna Zhou et al."Baicalein and hydroxypropyl-γ-cyclodextrin complex in poloxamer thermal sensitive hydrogel for vaginal administration."Int J Pharmaceut. 2013 Sep;454:125

• 42. [IF=6.057] Jiantong Qiao et al."Sensitive determination of baicalein based on functionalized graphene loaded RuO2 nanoparticles modified glassy carbon electrode."Talanta. 2018 Oct;188:714

• 41. [IF=7.808] Jianhua Li et al."Production of plant-specific flavones baicalein and scutellarein in an engineered E. coli from available phenylalanine and tyrosine."Metab Eng. 2019 Mar;52:124

• 40. [IF=9.381] Qiuna Zhou et al."Preparation and characterization of inclusion complexes formed between baicalein and cyclodextrins."Carbohyd Polym. 2013 Jun;95:733

• 39. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https://

• 38. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https://doi.org/10.1016/j.jpba.2019.11

• 37. Zhou, Qiuna, et al. "Baicalein and hydroxypropyl-γ-cyclodextrin complex in poloxamer thermal sensitive hydrogel for vaginal administration." International journal of pharmaceutics 454.1 (2013): 125-134.https://doi.org/10.1016/j.ijpharm.2013.07.006

• 36. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https://doi.org/10.1002/clen.201300193

• 35. Qiu, Jingying, et al. "Assessment of a bifendate derivative bearing a 6, 7-dihydro-dibenzo [c, e] azepine scaffold as a potential anti-metastatic agent." MedChemComm 9.11 (2018): 1826-1830.https://doi.org/10.1039/C8MD00294K

• 34. Xin-Guo Z, Kou F, Guo-Di M, Tang P, Zhong-Duo Y. Pharmacokinetics and pharmacodynamics of a novel Acetylcholinesterase Inhibitor, DMNG-3. Acta Neurobiologiae Experimentalis. 2016 ;76(2):117-124. DOI: 10.21307/ane-2017-011. PMID: 27373949.

• 33. Yang, Zongchun, et al. "Baicalein improves glucose metabolism in insulin resistant HepG2 cells." European journal of pharmacology 854 (2019): 187-193.https://doi.org/10.1016/j.ejphar.2019.04.005

• 32. Tang W, Li W, Yang Y, Lin X, Wang L, Li C, Yang R. Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus). Foods. 2021; 10(6):1183. https://doi.org/10.3390/food

• 31. Shi, Liang, et al. "Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC." Biochemical pharmacology 150 (2018): 9-23.https://doi.org/10.1016/j.bcp.2018.01.026

• 30. 紀萬里,周澤華,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏瀉心湯化學成分[J].藥物分析雜志,2020,40(10):1736-1750.

• 29. 馬宗敏,苗文麗,劉佳,何培,孫國強,裴林.黃芩內(nèi)生真菌發(fā)酵黃芩苷生成千層紙素A的代謝途徑及轉(zhuǎn)化條件研究[J].天然產(chǎn)物研究與開發(fā),2020,32(11):1928-1936.

• 28. 沈亮亮,李勇,周明,譙英固,孫震曉.增強人尿源性干細胞干性的中藥小分子活性成分篩選[J].中國新藥雜志,2020,29(24):2839-2845.

• 27. 李壯壯, 張靜, 趙紹哲,等. 指紋圖譜與化學計量學結(jié)合優(yōu)選柴胡桂枝顆粒水提工藝[J]. 中成藥, 2018, v.40(08):199-203.

• 26. 范琳琳, 王英, 黃自蘇,等. 外源添加物質(zhì)對黑莓清汁花色苷穩(wěn)定性和抗氧化活性的影響[J]. 食品工業(yè)科技, 2019, v.40;No.420(04):62-67.

• 25. 楊夢玲, 尤朋濤, 何麗珊,等. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動力學[J]. 中國中藥雜志, 2018, 43(18).

• 24. 陳智. 金銀花和黃芩不同煎煮方式化學成分變化及抗病毒作用比較[J]. 中華中醫(yī)藥雜志, 2019, v.34(10):129-133.

• 23. 任永申, 鄧鑫, 雷蕾,等. 基于抑菌效應(yīng)成分指紋譜的黃芩質(zhì)量評價研究[J]. 藥學學報, 2019, 054(012):2155-2161.

• 22. 李云靜, 張建逵, 趙玥,等. 黃芩藥材顏色及其有效成分的相關(guān)性[J]. 中國醫(yī)藥工業(yè)雜志, 2017(7).

• 21. 馬宗敏, 劉佳, 段緒紅,等. 黃芩苷發(fā)酵轉(zhuǎn)化成黃芩素和千層紙素A的黃芩內(nèi)生真菌的篩選及鑒定[J]. 中國實驗方劑學雜志, 2019(9):166-171.

• 20. 吳逸晨, 謝輝, 毛春芹,等. 復(fù)方甘草清瘍合劑HPLC指紋圖譜[J]. 中成藥, 2019, 041(009):2251-2256.

• 19. 袁杰, 李錟, 周利,等. 基于超高效液相色譜法和色差儀法的黃芩藥材質(zhì)量評價[J]. 世界中醫(yī)藥, 2019.

• 18. 柴沖沖,曹妍,毛民,王靖越,劉娜,李欣欣,張凱,陳東玲,魏龍吟,尹怡慧,李飛.基于電子舌技術(shù)評價黃芩酒炙前后滋味變化及其在黃芩飲片鑒別中的應(yīng)用研究[J].中國中藥雜志,2020,45(11):2552-2559.

• 17. 張慧, 李思雨, 馮宏玲,等. 基于效應(yīng)成分指數(shù)的雙黃連制劑質(zhì)量控制研究[J]. 藥學學報, 2019, 054(012):2149-2154.

• 16. 柴沖沖 毛民 袁金鳳 等. 不同方法軟化切制后的黃芩飲片顏色與5種黃酮類成分含量的相關(guān)性研究[J]. 中國中藥雜志 2019.

• 15. 郭凈潔, 王崇, 張維甲,等. 黃芩素與黃芩苷聯(lián)合用藥對口腔鱗癌細胞增殖,遷移的影響[J]. 口腔醫(yī)學, 2020, 040(005):393-398.

• 14. 程燕, 曲紹風, 李福偉,等. 黃芩中4種黃酮類化合物的亞臨界水提取研究[J]. 山東科學, 2013(03):11-14.

• 13. 劉媛媛, 劉陶, 吳玉梅,等. 基于雌激素受體調(diào)節(jié)Nrf2-ARE通路的黃芩中抗氧化成分的篩選[J]. 中國藥理學通報, 2019, 035(006):822-827.

• 12. 商利娜, 王亞靜, 趙鑫,等. 基于譜-效關(guān)系探究黃芩抑制白色念珠菌的質(zhì)量標志物[J]. 中成藥, 2020, 042(005):1357-1361.

• 11. 李淑嬌, 王宇卿. 基于HPLC-Q-TOF/MS法的黃芩血清藥物化學分析[J]. 中成藥, 2019, 41(03):117-122.

• 10. 陳慧潔 楊亞楠 丁輝 等. 養(yǎng)陰利咽半生制劑袋泡茶的制備及優(yōu)化[J]. 天津中醫(yī)藥大學學報 2019 38(01):78-83.

• 9. 王東超 魏穎 高佳琪 孫文 秦靈靈 蘭衛(wèi) 石浩霞 李博 徐暾海 劉銅華.HPLC同時測定糖痹康顆粒中黃芩苷、漢黃芩苷、黃芩素、漢黃芩素的含量[J].吉林中醫(yī)藥 2017 37(05):513-517.

• 8. 王健, 李健, 王勇,等. 黃芩素通過抑制PI3K/AKT/mTOR 通路誘導(dǎo)膀胱癌細胞凋亡[J]. 山東大學學報(醫(yī)學版), 2019(9).

• 7. 溫紹霞, 武軍駐. 黃芩素對肺炎克雷伯菌生長及生物膜形成能力影響的研究[J]. 檢驗醫(yī)學與臨床, 2013(20):2707-2708.

• 6. 張瀛, 皮佳鑫, 李雯,等. 黃芩素-茶堿共晶的溶劑體系篩選及體外溶出度評價[J]. 天津中醫(yī)藥, 2020, v.37(01):98-103.

• 5. 周秋娜, 尉小慧, 王崢濤. 黃芩素-羥丙基-γ-環(huán)糊精包合物制備工藝研究[J]. 上海中醫(yī)藥雜志, 2013, 047(008):82-85.

• 4. 陳智, 田景振. 基于模擬炮制法研究黃芩炒炭前后苷類成分的變化[J]. 山東中醫(yī)藥大學學報, 2020, v.44;No.242(01):85-90.

• 3. 岑建斌 梁志森 區(qū)碩俊 黃嘉樂 李秀英 林青蘭 陳玉珍 劉炘杰 林森煜.分散固相萃取-高效液相色譜-串聯(lián)質(zhì)譜法同時測定保健品片劑中5種黃芩素類化合物[J].色譜 2020 38(06):672-678.

• 2. 李云靜 張建逵 王冰 等. 不同產(chǎn)地黃芩藥材中黃芩苷等5種黃酮類成分含量的比較[J]. 時珍國醫(yī)國藥 2016 027(012):2985-2988.

• 1. 馬宗敏 苗文麗 段緒紅 等. 一株發(fā)酵轉(zhuǎn)化黃芩苷菌株的篩選及鑒定[J]. 天然產(chǎn)物研究與開發(fā) 2019 31(02):49-54.

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *