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• 介紹：

  丁酰膽堿酯酶(BChE)是一種絲氨酸水解酶，結(jié)構(gòu)上類似于乙酰膽堿酯酶(AChE)，但具有不同的底物特異性和抑制劑敏感性。該酶是由4個(gè)相同亞基（每個(gè)110kDa）組成的四聚體糖蛋白，又稱為擬膽堿酯酶(pseudocholinesterase)。它在肝臟中合成，分布于血液、神經(jīng)肌肉接頭突觸、神經(jīng)膠質(zhì)細(xì)胞和白質(zhì)軸突中。

  活力：≥10 units/mg protein。

  分子量：tetramer 440 kDa。

  來源：馬血清。

  酶活定義：一個(gè)單位將在 pH8.0，37°C 下每分鐘將1.0μ 摩爾丁酰膽堿水解為膽堿和丁酸鹽。使用丁酰膽堿作為底物獲得的活性是使用乙酰膽堿獲得的活性的約 2.5 倍。

• 溶解性： cold  water:  soluble60  U/mL

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 12. [5.3] Zhang Yue et al."Ratiometric fluorescence and colorimetric strategies for assessing activity of butyrylcholinesterase in human serum using g-C3N4 nanosheets, silver ion and o-phenylenediamine."MICROCHIMICA ACTA.2024 Jul;191(7):1-9

• 11. [IF=7.3] Lei Wang et al."Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer’s Disease."JOURNAL OF MEDICINAL CHEMISTRY".2024;XXXX(XXX):XXX-XXX

• 10. [1.813] Liang Liu et al."Phytochemical Profiles and Bioactivities of Parnassia palustris L.."European Journal of Integrative Medicine.2022 Nov;:102207

• 9. [IF=6.911] Wen-da Zhang et al."A far-red/near-infrared fluorescence probe with large Stokes shift for monitoring butyrylcholinesterase (BChE) in living cells and in vivo."ANALYTICA CHIMICA ACTA.2022 Dec;1235:340540

• 8. [IF=3.889] Shuang Miao et al."Aaptamine – a dual acetyl – and butyrylcholinesterase inhibitor as potential anti-Alzheimer’s disease agent."PHARMACEUTICAL BIOLOGY

• 7. [IF=9.231] Xiaowei Mu et al."Branched poly(ethylenimine) carbon dots-MnO2 nanosheets based fluorescent sensory system for sensing of malachite green in fish samples."FOOD CHEMISTRY.2022 Nov;394:133517

• 6. [IF=6.514] Bohang Zhou et al."Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase."Eur J Med Chem. 2020 Aug;200:112415

• 5. [IF=7.46] Yue Zhang et al."A dual-signal sensing platform based on nanosheet materials for ratiometric fluorescence and colorimetric detection of enzyme activities in human blood."Sensor Actuat B-Chem. 2021 Nov;346:130531

• 4. [IF=4.379] Zhou Bohang et al."New 2-Aryl-9-methyl-β-carbolinium salts as Potential Acetylcholinesterase Inhibitor agents: Synthesis, Bioactivity and Structure–Activity Relationship."Sci Rep-Uk. 2018 Jan;8(1):1-18

• 3. [IF=6.543] Zhang Jing et al."Studies of the Anti-amnesic Effects and Mechanisms of Single and Combined Use of Donepezil and Ginkgo Ketoester Tablet on Scopolamine-Induced Memory Impairment in Mice."Oxid Med Cell Longev. 2019;2019:8636835

• 2. 郝雅茹,李亭,張薇,李書國.基于石墨烯的丁酰膽堿酯酶傳感器法快速測定水產(chǎn)品中的孔雀石綠[J].現(xiàn)代食品科技,2020,36(12):267-273.

• 1. 王苗苗, 嚴(yán)歡, 田合,等. 薰衣草提取物的體外抗氧化活性及酶抑制活性研究[J]. 食品工業(yè)科技, 2019, 40(16).

輸入產(chǎn)品批號：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *