• 提示：詳情請下載說明書。

• 介紹：

• 分子量：約128 KDa 。

• 活力定義：One unit causes an increase in the absorbance at 280nm of 0.001 per minute at 25℃，PH 6.5，using L-tryosine as substrate.

• 適宜溫度25℃。

• 最佳PH：6.0～7.0。

• 性狀：粉末。

• 介紹：可催化含酚基化合物(如酪氨酸、酚類化合物等)氧化成醌的酶。此類酶廣泛存在于自然界，植物中分布很廣，如馬鈴薯、茶葉、漆樹乳汁中含量相當高。高等動物的皮膚、毛發(fā)、角膜中的黑色素也是由于此酶氧化酪氨酸所生成的產(chǎn)物。蘑菇等菌類及其他微生物中也產(chǎn)生此類酶。通常從野蘑菇中提取，系生物催化劑之一，含有銅離子的蛋白質(zhì)。等電點<5.0；含氮量約13.6％。含銅量約0.25％。紫外吸收峰在273nm和330nm處。

• 溶解性： 產(chǎn)品可以用水或者緩沖液溶解，建議現(xiàn)配現(xiàn)用，用不完部分盡量4℃儲存，盡快使用。溶液形式不能凍融，凍融會導致失活。

• 儲存條件： -20℃

• 用途： 它催化酪氨酸氧化成多巴和多巴進一步氧化成能產(chǎn)生黑色素的前體物——多巴醌。

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

• 70. [4.8] Huiyun Pang et al."Mushroom polyphenol oxidase inactivation kinetics and structural changes during radiofrequency heating."Food Bioscience.2024 Dec;62:105136

• 69. [4.9] Haisheng Lin et al."In Vitro In Silico Screening Strategy and Mechanism of Novel Tyrosinase Inhibitory Peptides from Nacre of Hyriopsis cumingii."Marine Drugs.2024 Sep;22(9):420

• 68. [7] Qianqian Luo et al."Oxidation of tea polyphenols promotes chlorophyll degradation during black tea fermentation."FOOD RESEARCH INTERNATIONAL.2024 Nov;196:115016

• 67. [1.8] Cai-Cai Liang et al."Screening and characterization of cosmetic efficacy components of Terminalia chebula based on biological activity-guided methodology."BIOMEDICAL CHROMATOGRAPHY.2024 Aug;:e5974

• 66. [4.9] Fei Li et al."In Silico Identification and Molecular Mechanism of Novel Tyrosinase Inhibitory Peptides Derived from Nacre of Pinctada martensii."Marine Drugs.2024 Aug;22(8):359

• 65. [1.1] Zhu Wang et al."Tyrosinase inhibition, molecular docking and molecular dynamics simulation studies of anthraquinone derivative from aloe vera as potential pigmentation dermatosis and anti-food browning agent."SPECTROSCOPY LETTERS.

• 64. [3] Jian Xu et al."Comparative study on metabolite variations of two rose teas by plant metabolomics and revealing their skin-whitening candidates by spectrum–effect relationship analysis."PHYTOCHEMICAL ANALYSIS.2024 Jul;:

• 63. [4.8] Qianqian Chen et al."Inhibitive Mechanism of Loquat Flower Isolate on Tyrosinase Activity and Melanin Synthesis in Mouse Melanoma B16 Cells."Biomolecules.2024 Aug;14(8):895

• 62. [5.3] Zhang Yue et al."Ratiometric fluorescence and colorimetric strategies for assessing activity of butyrylcholinesterase in human serum using g-C3N4 nanosheets, silver ion and o-phenylenediamine."MICROCHIMICA ACTA.2024 Jul;191(7):1-9

• 61. [6] Zhuang Yuxiu et al."A novel tyrosinase inhibitory peptide obtained from Sipunculus nudus gelatin hydrolysate: Preparation, identification, and action mechanism."LWT-FOOD SCIENCE AND TECHNOLOGY.2024 Jun;202:116293

• 60. [IF=3.8] Hong-mao Qiu et al."Bionic synthesis of novel monoterpenoid indole alkaloid-like analogs with tyrosinase inhibition activity based on loganetin."JOURNAL OF MOLECULAR STRUCTURE".2024 Sep;1312:138608

• 59. [IF=8.1] Yanbing Wen et al."Inactivation of polyphenol oxidase by low intensity DC field: Experiment and mechanism analysis via molecular dynamics simulation and molecular docking."FOOD RESEARCH INTERNATIONAL".2024 Apr;:114325

• 58. [IF=3.4] Tingting Yan et al."Salty treatment increased bioactive compounds accumulation during agarwood development in Aquilaria sinensis trees."FITOTERAPIA".2024 Mar;:105901

• 57. [IF=5.4] Xuemei Yu et al."Multi-technology integrated network pharmacology-based study on phytochemicals, active metabolites, and molecular mechanism of Psoraleae Fructus to promote melanogenesis."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;:117755

• 56. [IF=4.4] Yiwan Zheng et al."Enhancing thermostability of alkaline κ-carrageenase from Pseudoalteromonas tetraodonis by rational design of disulfide bonds."PROCESS BIOCHEMISTRY.2023 Nov;134:304

• 55. [IF=8] Donglu Fang et al."Metabolomic approach: Postharvest mushroom (Agaricus bisporus) browning inhibited by nanocomposite packaging materials."Food Packaging and Shelf Life.10.1016/j.fpsl.2023.101186

• 54. [IF=2.6] Liu Yuansong et al."Study on biological dyeing technology for directional pattern regulation of poplar infected by Lasiodiplodia theobromae."European Journal of Wood and Wood Products.2023 Aug;:1-11

• 53. [IF=3.9] Chen Fangfang et al."Characterization of tea (Camellia sinensis L.) flower extract and insights into its antifungal susceptibilities of Aspergillus flavus."BMC Complementary Medicine and Therapies.2023 Dec;23(1):1-13

• 52. [IF=16.6] Xu Shichao et al."A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function."Nature Communications.2023 Jul;14(1):1-14

• 51. [IF=3.3] Zhang Le et al."Biotransformation of ginsenoside Rb1 and Rd to four rare ginsenosides and evaluation of their anti-melanogenic effects."Journal of Natural Medicines.2023 Jun;:1-14

• 50. [IF=5.2] Wenhan Xu et al."Physicochemical and preservative properties of tyrosinase-crosslinked sodium caseinate-EGCG-carboxymethyl chitosan composite packaging: Comparison of blended and layer-by-layer films."Food Bioscience.2023 Jun;:102831

• 49. [IF=5.2] Zhen Ge et al."Tyrosinase Inhibitory Peptides from Enzyme Hydrolyzed Royal Jelly: Production, Separation, Identification and Docking Analysis."Foods.2023 Jan;12(11):2240

• 48. [2.667] Liu, Yuansong et al."Biological control of melanin biosynthesis pathway on prolific and pleochromatic induction of Lasiodiplodia theobromae."ARCHIVES OF MICROBIOLOGY.2023 Jan;205(1):1-12

• 47. [3.614] Liqun Fang et al."High-performance liquid chromatography micro-fraction bioactive evaluation combined with countercurrent chromatographic separation of antioxidants from Citrus peel and their tyrosinase inhibition activities."JOURNAL OF SEPARATION SCIENCE

• 46. [10.723] Jiaxing Hu et al."Understanding the impact of pectin on browning of polyphenol oxidation system in thermal and storage processing."CARBOHYDRATE POLYMERS.2023 May;307:120641

• 45. [8.025] Jingsi Li et al."Biomimetic multifunctional hybrid sponge via enzymatic cross-linking to accelerate infected burn wound healing."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Jan;225:90

• 44. [4.927] Kunyi Liu et al."An In Vitro Catalysis of Tea Polyphenols by Polyphenol Oxidase."MOLECULES.2023 Jan;28(4):1722

• 43. [6.317] Pantian Huang et al."Rapid Screening of Novel Tyrosinase Inhibitory Peptides from Pearl Shell Meat Hydrolysate by Molecular Docking and The Anti-melanin Mechanism."Food & Function.2022 Dec;:

• 42. [IF=6.51] Xuepeng Lv et al."High Skin Permeation, Deposition and Whitening Activity Achieved by Xanthan Gum String Vitamin C Flexible Liposomes for External Application."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2022 Oct;:122290

• 41. [IF=6.056] Hui Ma et al."Effects of microwave irradiation of Fagopyrum tataricum seeds on the physicochemical and functional attributes of sprouts."LWT-FOOD SCIENCE AND TECHNOLOGY.2022 Jul;:113738

• 40. [IF=2.528] Liu Yuansong et al."Study on infection behavior and characteristics of poplar wood dyed by Lasiodiplodia theobromae."European Journal of Wood and Wood Products.2022 Jun;:1-13

• 39. [IF=13.273] Junping Ma et al."Ultrasensitive electrochemical determination of bisphenol A in food samples based on a strategy for activity enhancement of enzyme: layer-by-layer self-assembly of tyrosinase between two-dimensional porphyrin metal-organic framework nanof

• 38. [IF=4.24] Qun Yu et al."The inhibition mechanisms between asparagus polyphenols after hydrothermal treatment and tyrosinase: A circular dichroism spectrum, fluorescence, and molecular docking study."Food Bioscience. 2022 May;:101790

• 37. [IF=7.46] Xiaochun Wang et al."A near-infrared fluorescent chemosensor with a remarkably large Stokes shift for the ultrasensitive detection of tyrosinase activity and bioimaging in living cells and mouse xenograft model."Sensor Actuat B-Chem. 2022 Mar;354:131211

• 36. [IF=6.312] Wei Wang et al."Kojic Acid Showed Consistent Inhibitory Activity on Tyrosinase from Mushroom and in Cultured B16F10 Cells Compared with Arbutins."Antioxidants-Basel. 2022 Mar;11(3):502

• 35. [IF=2.881] Yuansong Liu et al."The Action Difference of Lasiodiplodia theobromae on Infecting and Dyeing Poplar Wood in Spatial Growth."Coatings. 2021 Aug;11(8):985

• 34. [IF=3.171] Nueraili Maimaiti et al."Ethanol shock enhances the recovery of anthocyanin from lowbush blueberry."Chinese J Chem Eng. 2020 Dec;28:3096

• 33. [IF=3.247] Cheng Wang et al."Effects of polyphenol oxidases on proteolysis and lipolysis during ensiling of Moringa oleifera leaves with or without pyrocatechol."Anim Feed Sci Tech. 2021 May;275:114870

• 32. [IF=3.935] Cong-Peng Zhao et al."Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract."J Pharmaceut Biomed. 2021 Jan;193:113743

• 31. [IF=4.098] Jia An et al."Carbon dots-based dual-emission ratiometric fluorescence sensor for dopamine detection."Spectrochim Acta A. 2020 Dec;243:118804

• 30. [IF=4.142] Li Cong et al."A fluorescence strategy for monitoring α-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission."Anal Bioanal Chem. 2021 Apr;413(9):2553-2563

• 29. [IF=4.36] Chu Chu et al."A novel high-resolution monophenolase/diphenolase/radical scavenging profiling for the rapid screening of natural whitening candidates from Peaonia lactiflora root and their mechanism study with molecular docking."J Ethnopharmacol. 2022 Jan

• 28. [IF=4.641] Fei Qu et al."Aggregation-induced emission of lead halide perovskites modulated by dispersed/aggregated gold nanoparticles for application in the detection of dopamine."Mater Res Bull. 2021 Oct;142:111405

• 27. [IF=4.749] Wei Peng Qiang et al."Mussel Adhesive Mimetic Silk Sericin Prepared by Enzymatic Oxidation for the Construction of Antibacterial Coatings."Acs Biomater Sci Eng. 2021;7(7):3379–3388

• 26. [IF=4.952] Qun Yu et al."Enhancing the antityrosinase activity of saponins and polyphenols from Asparagus by hot air coupled with microwave treatments."Lwt Food Sci Technol. 2020 Apr;124:109174

• 25. [IF=4.952] Yifan Gui et al."Roles of four enzyme crosslinks on structural, thermal and gel properties of potato proteins."Lwt Food Sci Technol. 2020 Apr;123:109116

• 24. [IF=5.279] Xueqi Li et al."Enzymatic and Nonenzymatic Conjugates of Lactoferrin and (?)-Epigallocatechin Gallate: Formation, Structure, Functionality, and Allergenicity."J Agr Food Chem. 2021;69(22):6291–6302

• 23. [IF=7.514] Qun Yu et al."Understanding the combined effect and inhibition mechanism of 4-hydroxycinnamic acid and ferulic acid as tyrosinase inhibitors."Food Chem. 2021 Aug;352:129369

• 22. [IF=7.514] Hui Teng et al."Folium nelumbinis (Lotus leaf) volatile-rich fraction and its mechanisms of action against melanogenesis in B16 cells."Food Chem. 2020 Nov;330:127030

• 21. [IF=7.514] Qun Yu et al."New insights into antityrosinase capacity and polyphenols of asparagus during hydrothermal treatments."Food Chem. 2020 Oct;326:126968

• 20. [IF=7.711] Man Wang et al."3-Aminophenyl Boronic Acid Functionalized Quantum-Dot-Based Ratiometric Fluorescence Sensor for the Highly Sensitive Detection of Tyrosinase Activity."Acs Sensors. 2020;5(6):1634–1640

• 19. [IF=4.464] Fang Yuan et al."Split photoelectrochemistry for the immunoassay of α-fetoprotein based on graphitic carbon nitride."J Electroanal Chem. 2016 Dec;783:226

• 18. [IF=4.616] Zhongdi Tang et al."A conjugated carbon-dot–tyrosinase bioprobe for highly selective and sensitive detection of dopamine."Analyst. 2019 Jan;144(2):468-473

• 17. Zhang, Fangmei, et al. "Dopamine-modified Mn-doped ZnS quantum dots fluorescence probe for the sensitive detection of tyrosinase in serum samples and living cells imaging." Sensors and Actuators B: Chemical 256 (2018): 1069-1077.https://doi.org/10.1016/j.s

• 16. Tang, Zhongdi, et al. "A conjugated carbon-dot–tyrosinase bioprobe for highly selective and sensitive detection of dopamine." Analyst 144.2 (2019): 468-473.DOI: 10.1039/C8AN01659C

• 15. Cong-Peng Zhao, Shi-Jun Yin, Guo-Ying Chen, Yuan Wang, Hua Chen, Jing Zhao, Feng-Qing Yang, Adsorbed hollow fiber immobilized tyrosinase for the screening of enzyme inhibitors from Pueraria lobata extract, Journal of Pharmaceutical and Biomedical Analysis,

• 14. Teng, Hui, et al. "Folium nelumbinis (Lotus leaf) volatile-rich fraction and its mechanisms of action against melanogenesis in B16 cells." Food Chemistry 330 (2020): 127030.https://doi.org/10.1016/j.foodchem.2020.127030

• 13. 彭穎,何婉鶯,范鑫,盧琪,何小燕,潘思軼.柚皮苷二氫查爾酮的抗氧化活性研究[J].中國食品學報,2021,21(02):45-54.

• 12. 劉瑞,李莉,李瑋,刁娟娟.異丙酚分子印跡聚合物微球的制備工藝與表征研究[J].新疆醫(yī)科大學學報,2020,43(11):1495-1499.

• 11. 張雷,馮晨,楊淑琴,郭秀茹.一款抗紫外線和抗藍光的復合植物提取液功效研究[J].日用化學品科學,2021,44(04):44-48.

• 10. 陳榮達,史玉蕊,劉桂明,陶彥舟,范陽揚,李麗.紫娟茶花青素提取物抑制酪氨酸酶活性研究[J].長春師范大學學報,2020,39(12):90-93.

• 9. 祝上賓,王英颯,敬凡塵,劉潤東,何靜,雷建都.熊果苷磷脂復合物的制備、表征及理化性質(zhì)研究[J].中草藥,2020,51(22):5698-5704.

• 8. 李俊強, 李星辰, 劉曉靜. 甘草總皂苷生物轉(zhuǎn)化與抑制酪氨酸酶活性研究[J]. 中國藥事, 2018, 032(002):234-241.

• 7. 湯翠, 王明力, 趙婕,等. 高酸值薏米糠油脫酸技術及其活性研究[J]. 中國油脂, 2017, 42(003):18-23.

• 6. 楊芳, 王藝涵, 袁辛銳,等. 銀耳多糖醇沉級分對酪氨酸酶的抑制作用[J]. 食品工業(yè), 2020, v.41;No.282(03):6-9.

• 5. 孔令悅,向華,唐克華,董愛文,唐忠海.白及多糖脂質(zhì)體的制備及對酪氨酸酶活性的影響[J].食品與機械,2020,36(05):160-163+174.

• 4. 楊娜 趙雨晴 張帥 等. 響應面法優(yōu)化提取白附子美白成分的工藝研究[J]. 哈爾濱商業(yè)大學學報(自然科學版) 2019 v.35;No.159(04):12-15+19.

• 3. 于麗娟 吳麗華 王金香 等. 余甘子提取物抗氧化能力分析和對酪氨酸酶活性的影響[J]. 西南農(nóng)業(yè)學報 2020(7).

• 2. 曹思瑤 宋卓 林鑫宇 等. 烏拉爾甘草不同溶劑提取物的美白活性比較研究[J]. 長春中醫(yī)藥大學學報 2019 035(001):140-143 146.

• 1. 段坤峰 尹星爍 鄭旭光 等. 中空纖維固定化酪氨酸酶法快速篩選北沙參中抗黑色素生成活性成分[J]. 中國臨床藥理學雜志 2019.

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *