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• 產品描述： Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.

• 靶點： NOD

• 體內研究：
  Molsidomine (50, 100, 250 μg/kg) reduces coronary flow while the coronary resistance remains unaffected by molsidomine. Molsidomine decreases myocardial oxygen consumption. Heart rate and contractility remains unchanged by molsidomine. Stroke volume and cardiac output fall after molsidomine. The fall in blood pressure after molsidomine follows the reduction in cardiac output as sequel of lowered preload and venous return to the heart

• 參考文獻：
  1.Volker B. Fiedler, et al. Naunyn-Schmiedeberg's Archives of Pharmacology. 1981, 317(1):71-77.

• 溶解性： Ethanol:21  mg/mL(86.7  mM)    DMSO:45  mg/mL  (185.8  mM)    H2O:9  mg/mL  (37.15  mM)

• 保存條件： 2-8°C,避光

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	4.128 ml	20.642 ml	41.283 ml
  5 mM	0.826 ml	4.128 ml	8.257 ml
  10 mM	0.413 ml	2.064 ml	4.128 ml
  50 mM	0.083 ml	0.413 ml	0.826 ml

• 注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

輸入產品批號：

本計算器可幫助您計算出特定溶液中溶質的質量、溶液濃度和體積之間的關系，公式為：

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *