• 提示：詳情請下載說明書。

• 產(chǎn)品描述： Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.

• 靶點： SIRT2:28 nM (IC50);SIRT1:98 μM (IC50);Sirtuin

• 體內(nèi)研究：
  TM inhibits tumor growth in mouse models of breast cancer. TM does not cause significant toxicity in mice and no significant weight loss is observed in TM-treated mice. S5H, the acetyl-a-tubulin level is moderately but statistically significantly increased in tumors from TM-treated mice compared with those from vehicle-treated mice, suggesting that TM indeed inhibits SIRT2 in vivo

• 參考文獻：
  1. Jing H, et al. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 2016 Mar 14;29(3):297-310.

• 溶解性： DMSO  :  ≥  32  mg/mL  (55.00  mM)    Ethanol  :  15.29  mg/mL  (26.28  mM;  Need  ultrasonic)

• 保存條件： -20℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	1.719 ml	8.593 ml	17.187 ml
  5 mM	0.344 ml	1.719 ml	3.437 ml
  10 mM	0.172 ml	0.859 ml	1.719 ml
  50 mM	0.034 ml	0.172 ml	0.344 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *